
Dr Siang Boon Koh
BSc (Pharm), PhD
Current positions
Senior Lecturer
School of Cellular and Molecular Medicine
Contact
Press and media
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Research interests
The Koh Laboratory investigates the mechanisms that enable tumour cells to adapt, survive, and resist therapy. By integrating molecular and cellular biology, imaging, multi-omics profiling, and AI-based computational strategies, we seek to elucidate how tumour-intrinsic programmes and tumour–host interactions shape tumour resilience. These insights will reveal actionable tumour-specific vulnerabilities that can be targeted to develop more effective and selective treatment strategies.
Enquiries from prospective graduate students and postdoctoral researchers are welcome.
Projects and supervisions
Research projects
8542 Research Grants 2025 Round 1 (Royal Society Ref: RG\R1\251160)
Principal Investigator
Managing organisational unit
School of Biochemistry and Biomedical SciencesDates
01/03/2025 to 31/05/2027
Thesis supervisions
Publications
Recent publications
25/03/2026Deciphering double-negative prostate cancer
Cell Communication and Signaling
cAMP response element–binding protein
Journal of Pharmacology and Experimental Therapeutics
CREB1-BCL2 drives mitochondrial resilience in RAS GAP-dependent breast cancer chemoresistance
Oncogene
Design, synthesis, molecular modeling, and antiproliferative evaluation of new 2-oxoindolin-3-ylidene thiazole derivatives
RSC Medicinal Chemistry
Interactions between radiotherapy resistance mechanisms and the tumor microenvironment
Critical reviews in oncology/hematology
